Oral morphine milligram equivalents, up to six concurrent opioids. Each line shows the factor that produced it.
Total daily MME
0
—
5090
Buprenorphine is listed but excluded from the total. The 2022 CDC table omits buprenorphine products: partial µ-agonism with a respiratory ceiling means dose does not carry full-agonist overdose risk, so an MME figure would mislead.
Methadone conversion method
Bands are the 2016 CDC values, still used by CMS in its Overutilization Monitoring System. The 2022 guideline replaced them with a single 4.7, which is what most PDMPs report. The band keys off total daily methadone dose. Neither is a titration tool.
Drug
Factor
Source
Changed in 2022: hydromorphone 4 → 5, tramadol 0.1 → 0.2, methadone 3 → 4.7. All other guideline-table factors unchanged from 2016.
Anticoagulant hold intervals
Two guidelines, shown side by side. They are different documents with different scopes — where they diverge, you are choosing, not looking up.
Guideline
These are two parallel documents, not an old one and a new one. Both are current ASRA publications from different author groups. Neither replaced the other. The 2025 paper replaced the 2018 regional guideline (4th ed) — it did not replace the pain guideline, and its own introduction points to a separate document for interventional pain procedures.
Planned procedureAgents the patient is taking
Patients at high bleeding risk undergoing a low- or intermediate-risk procedure are managed as intermediate or high respectively. Cervical facet MBNB/RFA sits at intermediate because of neck vascularity. Peripheral neuromodulation is low to intermediate depending on the target's relation to critical vessels. Risk tiers are a 2018 construct — the 2025 regional guideline does not use them.
Steroid equivalence & load
Anti-inflammatory equivalence between injectable corticosteroids, particulate status by agent, and a running cumulative total for one patient.
Convert
Route safety
Cumulative load — this patient
Add each injection over the period you care about. Nothing is saved; this clears when you close the tool.
Procedure room
Local anesthetic ceilings, LAST rescue, sedation titration, and reversal. Enter weight once; every panel updates.
View
Quick answer
All agents at this weight
Values are the conventional manufacturer-labeling ceilings, capped at the absolute maximum where one applies. They are not evidence-based thresholds: LAST has occurred well below these numbers, and site vascularity (intercostal > caudal > epidural > peripheral) drives peak plasma level more than total milligrams. Reduce in the elderly, cardiac, hepatic, or pregnant patient.
LAST — lipid emulsion 20%
Simultaneously: call for help · stop injecting · 100% oxygen, secure airway, avoid hypoxia and acidosis · benzodiazepine for seizure · ACLS if arrest.
Modified ACLS: epinephrine in small boluses, ≤1 mcg/kg. Avoid vasopressin, calcium channel blockers, beta blockers, and further local anesthetic. Propofol is not a substitute for lipid.
Monitor after stabilization: 2 h following a resolved seizure; 4–6 h following a resolved cardiovascular event. Alert the nearest cardiopulmonary bypass capability early if refractory.
Order of bolus versus infusion, and method of infusion, are not critical — give it early. Maximum total lipid 12 mL/kg.
Moderate sedation — titration
The combination is the danger, not either drug. Benzodiazepine plus opioid produces respiratory depression out of proportion to either alone. Give one agent, wait its full peak, then reassess before giving the other. Most procedural sedation catastrophes are stacked doses given before peak effect.
Reduce initial dose and total by roughly half in the elderly, debilitated, hepatic or renal impairment, or anyone with sleep apnea. Continuous capnography and pulse oximetry, and someone whose only job is monitoring the patient.
Reversal
Opioid taper planner
Percentages are of the original dose, which is how CDC and HHS express them. Schedules can be generated from an MME figure, from the actual tablets, or from patch strengths.
Mode
Enter a total daily MME. Produces a percentage schedule — useful for planning, but the targets will not land on dispensable doses.
Current regimen
Enter each product the patient takes. Extended-release rows are tapered first by default.
Taper order
ER-first is the default. Reverse it when the immediate-release product is the one driving the problem.
Current fentanyl patch
All eight manufactured strengths are included: 12, 25, 37.5, 50, 62.5, 75, 87.5, 100 mcg/hr. The intermediate strengths exist specifically to allow titration and make a real taper possible — without them you are forced into 33–50% drops. Totals above 100 are achieved with combined patches.